Grapefruit Extraction Naringin (Citrus grandis 'Tomentosa' or Citrus grandis (L.) Osbeck) 10-98% HPLC

Detailed Product Description

Naringin
Product name: Naringin
Botanical Source: Naringin is the major flavonoid glycoside in grapefruit and gives grapefruit juice its bitter taste. It is metabolized to the flavanone naringenin in humans. Both naringenin and hesperetin, which are the aglycones of naringin and hesperidin, occur naturally in citrus fruits.
Part used: Fruitlet
Active Ingredient: Naringin
Formula: C14H12O3
Quality standard
  1.Appearance: Yellowish powder
  2.Mesh: 100% pass 80 mesh 
  3.Assay:Naringin 10% 95% 98% (HPLC)
  4.Sulphated Ash:≤1.0%
  5.Heavy metal:≤10ppm
  6.As:≤2ppm
  7.Residual Solvents:≤0.05ppm
  8.Total Plate Count: 1000CFU/gm
  9.Yeast&Mold: 100CFU/gm 
  10.Pathogens:Negative
Pharmacological Function
         A number of drugs that are known to be affected by the naringin in grapefruit include calcium channel blockers, estrogen,Anti-inflammatory, anti-virus, anti-mutagenic, anti-ulcer,

cardiovascular and cerebrovascular diseases.sedatives, medications for high blood pressure, allergies,AIDS, and cholesterol-lowering drugs.  
        Naringin exerts a variety of pharmacological effects such as antioxidant activity, blood lipid lowering, anticancer activity, and inhibition of selected drug-metabolizing cytochrome P450 enzymes, including CYP3A4 and CYP1A2, which may result in drug-drug interactions in vivo. Ingestion of naringin and relatedflavonoids can also affect the intestinal absorption of certain drugs, leading to either an increase or decrease in circulating drug levels. To avoid interferencewith drug absorption and metabolism, the consumption of citrus (esp. grapefruit) 
and other juices with medications is contraindicated. Naringin, followed by rutin,  was the most potent flavonoid inhibitor of VEGF release, which causes angiogenesis,out of 21 flavonoids.

Package: Double plastic-bag inside, aluminum foil bag paper or fiber drum  outside.

 N.W: 25kg/drum.
Storage :Store in cool and dry place.